This 6th edition reviews some of the most noteworthy developments in the field, particularly in epileptic syndromes, but also focuses on the genetic aspects of the syndromes and their development. Progress brought about by advances in neuroimaging is also discussed in addition to specific etiologies such as parasitic diseases and immune and autoimmune diseases.The different backgrounds of the contributors - coordinators and authors - ensure that the book's longstanding reputation for objectivity and seriousness, built over almost 35 years, remain well-deserved.This book written by the current leading specialists is recognized worldwide as the international reference in epilepsy.

Encephalopathy with Electrical Status Epilepticus during Sleep (ESES) was described almost 50 years ago; however its clinical spectrum and its boundaries, the diagnostic criteria, the pathophysiology and the therapeutic management are still debated. In the last years, clinical data, neurophysiological and imaging investigations, as well as genetic studies have renewed the interest on ESES. In addition, experimental findings from sleep research have opened fascinating perspectives on some possible pathophysiological mechanisms involved in this condition. These issues are presented and discussed in this book by clinicians, neurophysiologists, sleep physiologists and geneticists. They all have been working on ESES with the aim to provide an updated overview of this special syndrome in the light of recent research.